How Long Does It Take For Metformin To Work


Metformin is a primary drug for patients with newly developed Type 2 Diabetes Mellitus. Though the FDA disapproves, specialists can use it to prevent the development of diabetes in alarming patients.

Suppose your doctor prescribed you Metformin, then you will expect to see some result relieving your discomfort. But you may ask how long does it take for metformin to work? Well, it does take a long time, at least a week. Let’s find out more.

What is Metformin

How Long Does It Take For Metformin To Work

It is a drug approved by the US Food and Drug Administration to treat diabetes patients. It decreases blood glucose by reducing glucose production by the liver. Also, it enhances

insulin sensitivity of targeted cell. 

It is a pretty low-dose medication. Thus doctors prescribe it with a balanced diet and exercise plan.  Usually, the medicine is available on the market in 500 mg, 850 mg, and 1000 mg tablets. 

Metformin Working Process

Metformin works in our body in 3 stages. First, it decreases glucose absorption by GI (Gastro-Intestinal) Tract. Secondly, it decreases glucose production by the liver. And it stimulates target cells to respond with insulin hormone.

In a type 2 diabetes patient, the body can produce enough insulin that can reduce blood sugar. Yet, the problem remains the body can’t utilize the insulin. Therefore metformin enhances cell’s ability to react with insulin and absorb sugar to produce energy. 

How Long Does It Takes

Metformin is a quick-acting medication, so the effects start after 48 hours of taking a pill. But you won’t be able to notice significant effects before 5 to 7 days. So, take that it will need at least a week to show you positive results.

Also, this medicine can cause some side effect for which the doctors prescribe it in small dosage. Those who are newly counted Type 2 diabetes patients start with 500 mg tablet a day. As time goes by, the doctor may increase the dose to 850 mg and a maximum of 1500 mg per day.

That means if the patient has high-risk diabetes that could take him/her months to notice blood level change. 

Metformin Side Effects

Some patients have to take metformin for the rest of their lives. As this is a long-term medication for diabetes worldwide, some side effects seemed familiar. These are very normal discomfort for anyone and don’t require any medical care.

Most common side effects caused by Metformin

  • Diarrhea
  • Bloating
  • Stomach Ache
  • Constipation 
  • Nausea
  • Gas
  • Heartburn

These are pretty common, and your body will adjust as time goes. However, some rare side effects are noticed in some patients: Lactic Acidosis, Anaemia, and Hypoglycemia. It happens 6.8 out of 100000 people who take metformin. 

Best Time to Take Medicine

You should always take metformin after having a meal. Usually, doctors prescribe the medicine once a day. So taking it after dinner will make it better because the body rests and can not use sugar for generating energy. 


If you or your close one got Type 2 diabetes, don’t panic. Visit a doctor, and he should guide you. If you get metformin as the medication, I hope you know why. Also, as you know, how long does it take for metformin to work, so keep patience.

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