How long does ketamine stay in your system

Ketamine is injected into the muscle (IM or intramuscular) or a vein (IV or intravenous). The FDA has recently approved ketamine nasal spray to cure treatment-resistant depression.

This drug at lower dosage produces sedation and pain relief. But at higher doses, it produces hallucinatory effects and dissociation.

How long does ketamine stay in your system? Its effects can be noticed within seconds of administering this drug in IV form while IM form takes around 4 minutes.

How long does ketamine stay in your system?

Its effects might last around 5-30 minutes depending its administering method. Following administration, the liver metabolizes it quickly into less-active metabolites.

Around 90% is excreted in metabolite form through urine. Its half-life in children is around1-2 hours and in adults by 2.5 hours.

The drug from clinical viewpoint is eliminated after four to five half-lives. This means, most of it is out of an adult’s system in approximately 10-12.5 hours.

What factors determine how long does ketamine stay in your system?

Some factors are body mass, age, drug dosage, metabolic rate and how it is administered. These factors tend to affect significantly its duration as well as elimination time from the system.

What are the available treatment options?

Ketamine if abused for a prolonged time is likely to cause psychological dependence. If not taken, chronic users are likely to experience cravings, since the body is addicted to it. Withdrawal symptoms may last for about 4 to 6 days. It may include the following:

  • Appetite loss
  • Increased cravings for ketamine
  • Chills
  • Tiredness
  • Restlessness
  • Sweating
  • Anxiety
  • Tremors
  • Rapid and irregular heartbeat
  • Depression

Ketamine can be difficult to quit if using for a long time. For effective treatment options, you should consult a good rehab facility. In case, you plan to stop using it abruptly, then you are likely to experience discomfort and intense cravings.

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